KeepHealthCare.ORG – Risk-based breast cancer screening may reduce costs, overdiagnosis
Not offering breast cancer screening to low-risk women and implementing risk-stratified breast screening programs may improve the cost-effectiveness of screening programs and reduce over diagnosis, according to research published July 5 in JAMA Oncology.
The study, led by Nora Pashayan, MD, PhD, from the department of applied health research at the University College of London, examined how age-based breast cancer screenings can reduce death from while limiting overdiagnosis.
“Identifying risk-stratified screening strategies with a more favorable ratio of over diagnoses to breast cancer deaths prevented would improve the quality of life of women and save resources,” Pashayan et al. wrote. “Risk-stratified screening would require assessing risk of all women, which would entail additional costs, however these may be offset by eliminating repeated screening of women at lower risk and avoiding treatment of over diagnosed cancers.”
To evaluate the cost effectiveness and benefit-to-harm ratio of risk-stratified breast screening compared with standard age-based breast screening and no screening at all, Pashayan and colleagues created a “life-table model” of a hypothetical cohort that included 364,500 women in the U.K. aged 50 to 85 years old with follow-up at one year.